Osteoarthritis of the Knee
Arizona Research Center frequently conducts clinical studies focused on managing knee osteoarthritis. . Our research supports advancements in care while helping reduce the need for opioids in chronic pain management.
If you’re living with knee osteoarthritis, join our waiting list to be considered for upcoming research opportunities.
What is Osteoarthritis of the Knee?
Osteoarthritis of the knee is a condition where the protective cartilage in the knee joint breaks down over time. As the cartilage wears away, the bones can start to rub against each other, which may cause pain, swelling, stiffness, and even bone spurs. This can make everyday movements—like walking, climbing stairs, or standing up—more difficult and uncomfortable.
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Why Should I Participate?
Participating in an osteoarthritis of the knee study is a valuable way to contribute to the future of healthcare.
Volunteers may:
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Help advance life-saving treatments
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Contribute to medical breakthroughs
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Receive compensation for time and travel
These studies may include health screenings, lab work, or monitored visits depending on the design of the research.
All studies are conducted under the supervision of experienced medical professionals.

Who Can Participate?
To be added to our waiting list you must:
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Be in generally good health
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Be between the ages of 18–75 (age range may vary by study)
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Do not have a chronic or serious medical conditions.
We encourage people from all backgrounds and walks of life to apply—diversity is essential to better research.
What is a research study or clinical trial?
A research study or clinical trial is the process a potential new drug, device, procedure, or process goes through to prove that it is safe, tolerable and effective for the condition it is being studied for. Research studies are the only way to advance medicine for future generations.
Who can participate in a research study?
Each study has its own set of inclusion and exclusion criteria that a participant must meet before they are allowed to participate in a study. Patients from all backgrounds and walks of life are encouraged to participate.
What is Informed Consent?
Every participant in every research study must go through the informed consent process. During this, the trial doctor and research team go over what will happen in the study, what treatments you might get, how long the trial is expected to last, what happens during visits, the potential risks and benefits, and many other important facts about the study. Participants may withdraw their consent and discontinue the study at any time for any reason.
What is a Placebo?
A placebo looks like a treatment but does not have any active medicine in it. Researchers use placebos to help make sure any changes in the participants’ health are actually caused by the study treatment. You do not get to choose if you get the study treatment or the placebo, and you may not know if you get the placebo until after the study. Not all research studies use a placebo.
Why is Diversity Important?
If studies do not include diverse participants, we cannot know if treatments work for everyone who needs them. Studies only tell researchers how something works for the participants of that study, and they may not work the same in people of different races, ethnicities, ages, or sexes.
How am I Protected?
All research studies must follow federal laws and ethical guidelines, including HIPAA. Studies must also be approved by an expert group called an institutional review board (IRB) that helps make sure the trial is fair and as safe as possible, and that any risks to the participants are worth the potential benefits.